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Immigrants filing USCIS Form I-485 to apply for an adjustment of status sometimes need additional supplements and instructions, depending on their specific situations. If you are filing Form I-485 based on a U visa or a T visa, you need I-485 (Supplement E, Instructions for I-485, Supplement E). T visas are available to those who have been victimized by human trafficking while U visas are available to victims of some types of crimes. If either of these situations apply to you, you will need to download I-485 (Supplement E, Instructions for I-485, Supplement E) to get specific instructions for your case.